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British Journal of Radiology (1976) 49, 427-429
© 1976 British Institute of Radiology
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The British Journal of Radiology, Vol 49, Issue 581 427-429, Copyright © 1976 by British Institute of Radiology

ARTICLES

The limitations of 113Inm for plasma volume measurement

R Wootton

Previous authors have claimed that 113InmCl3 is a valid tracer for plasma volume measurement. However, careful measurements in haematologically normal volunteers and in rabbits, using 125I-labelled human serum albumin as a reference tracer, show that the results obtained with 113Inm-chloride, -citrate or -transferrin consistently over-estimate the plasma volume and are probably no better than can be predicted from the height and weight of the subject.




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