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British Journal of Radiology (1975) 48, 846-850
© 1975 British Institute of Radiology
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The British Journal of Radiology, Vol 48, Issue 574 846-850, Copyright © 1975 by British Institute of Radiology

ARTICLES

Clinical radiobiology of low dose-rate radiotherapy

J Dutreix and A Sahatchiev

Investigative irradiations of human skin have shown that the total dose required to obtain a dry desquamation does not increase with the duration of the irradiation as rapidly as it would be expected from the kinetics of repair of the sublethal injuries. This suggests that an additional mechanism, probably accumulation of the cells in a sensitive phase, occurs during a continuous irradiation with dose-rate higher than 150 rads/hour. This effect seems to vanish at smaller dose-rates.




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