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British Journal of Radiology (1975) 48, 465-469
© 1975 British Institute of Radiology
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The British Journal of Radiology, Vol 48, Issue 570 465-469, Copyright © 1975 by British Institute of Radiology

ARTICLES

Chronic Gaucher's disease: radiological findings in 17 South African cases

HS Myers, BJ Cremin, P Beighton and S Sacks

This paper reports radiological findings in a series of 17 South African patients with chronic (adult or non-neuronopathic) Gaucher's disease. Osteoarticular signs are briefly analysed on the basis of their pathogenesis. The visceral findings included an enormous calcified spleen and three cases with pulmonary lesions. Important advances have been made recently in diagnosing. Gaucher's disease and detecting carriers by demonstration of deficiency of beta-glucosidase. Radiographs are not diagnostic, but they may provide valuable clues to the nature and extent of lesions in bone, and they are essential in orthopaedic management of Gaucher's disease.


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