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The British Journal of Radiology, Vol 48, Issue 568 312-314, Copyright © 1975 by British Institute of Radiology
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JH Hendry
Crypts in the mouse small intestine show a diurnal rhythm in radiosensitivity and are most sensitive in the middle of the dark period, when mitotic activity in the crypt is high. Analysis of crypt survival on a cellular basis shows that the changes in cryptogenic cell radiosensitivity are dose-modifying between 1,000 and 1,450 rads gamma rays such that the DO value varies between 85 rads and 140 rads.
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