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Two Cases of Meigs' Syndrome

Isle of Wight Hospital Group

This excerpt was created in the absence of an abstract.

The syndrome described by Meigs (1937) consists of ascites and hydrothorax in association with an ovarian tumour. His original series was one of seven cases, all of which were fibromas. Since that time the syndrome has been described in association with most types of ovarian tumour, but only some 50 cases have been recorded in the literature. The occurrence of two cases in this Hospital Group within a few weeks of one another, therefore, appeared to merit recording. The importance of recognising the syndrome lies in two facts, (a) the condition is usually a benign one, and (b) the ascites and hydrothorax clear up immediately following removal of the tumour and repeated aspiration is unnecessary. These two points are well exemplified by our two cases. Case 1 is microscopically a cystadenocarcinoma; it is felt that this must be of very low malignancy as the patient has made an uninterrupted recovery and three months after operation is clinically perfectly well. Simon (1947) has emphasised that the syndrome should not be associated with potentially malignant tumours, but that it can occur followed by relief on removal of the tumour is illustrated by this case. A further case in association with cystadenocarcinoma has been published by Schenck and Eis (1938). Case 2 is microscopically a pseudomucinous cystadenoma. In both cases the hydrothorax had cleared 14 days after operation.