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Figure 1


Figure 1. (a) Total number of proliferating and dormant tumour cells as a function of time for the hyperfractionated (1.2 Gy twice daily, 5 days per week to the dose of 81.6 Gy, "HF-81.6") and accelerated hyperfractionated (1.6 Gy twice daily, 5 days per week to the dose of 54.4 Gy, "AHF-54.4") radiotherapy schedules. HF-81.6 is completed on day 46 after initiation of treatment whereas AHF-54.4 is completed on day 23. In all fractionation schedules considered in this paper, no radiation is administered on Saturdays or Sundays. (b) Total number of proliferating and dormant tumour cells as a function of time for the hyperfractionated (1.2 Gy twice daily, 5 days per week to the dose of 76.8 Gy, "HF-76.8") and accelerated hyperfractionated (1.6 Gy twice daily, 5 days per week to the dose of 48 Gy, "AHF-48") radiotherapy schedules. Both irradiation schedules start on the first day of the first week of treatment. HF-76.8 is completed on day 44 after initiation of treatment whereas AHF-48 is completed on day 19.