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Figure 4. This is the processed image demonstrating the microvascular map (based on integrating microbubble signals) within a 2.8 cm breast lesion (in a patient diagnosed with grade 2 invasive ductal carcinoma). Note the hypoechoic central region, which is assumed to represent a hypovascular area within the lesion). Image supplied by Anand Rattansingh, Research Radiographer, Imperial College and Hammersmith Hospital, with permission.