Figure 2. A 72-year-old man suspected to have prostate cancer based on a high serum prostate-specific antigen (36.9 ng ml^-1) level and a positive digital rectal examination. The systematic octant biopsy results were positive in the left peripheral zone and left inner gland. Gleason score=4+4. (a) Transrectal ultrasound (left) and power Doppler ultrasound (right) of the prostate gland. Hypoechoic foci are demonstrated in the left peripheral zone (arrows) and the left inner gland (arrowhead). An intensely abnormal Doppler signal is observed in hypoechoic foci. The Doppler signal in the far right lateral peripheral zone is a neurovascular bundle (asterisk). (b) T₂ weighted turbo spin echo image (4700/120) shows a low intensity lesion in the left peripheral zone (arrows) and left inner gland (arrowhead). (c) Early dynamic contrast-enhanced MRI shows strong enhancement in the low signal intensity lesion. (d) Regions of interest are superimposed on the source image of the left peripheral zone and left inner gland hypervascular lesions. (e) Time–intensity curves from the right and left peripheral zones. The left peripheral zone shows early, intense enhancement and was classified as Type A. The right peripheral zone shows delayed enhancement with no signal peak and was classified as Type C. The periodic fluctuations in the signal intensity curves are derived from respiratory motion artefacts produced by the abdominal wall.