Figure 1. Data from a 33-year-old male with a space-occupying lesion in the right paracentral lobule depicting statistically significant correlation (p<0.05, corrected for multiple comparisons) between finger movement and model haemodynamic response overlaid (in colour) on base echo-planar images (greyscale). (a) Activation can be attributed to primary motor, primary somatosensory and supplementary motor areas of the cortex within the left hemisphere following right hand movement. (b) Bilateral activation is detected following left hand movement. (c) Post-Gd-DTPA T₁ weighted spin-echo image depicting the anatomy at the level of the echo planar images (a) and (b). (d) Post-Gd-DTPA T₁ weighted spin-echo image showing the tumour.