Figure 6. Series of radiographs in a 69-year-old woman with metastatic deposits in L4 vertebra due to carcinoma of the breast. (a) Lateral radiograph shows mixed lytic-sclerotic involvement of a mildly compressed L4 vertebral body. (b) Slightly oblique prone radiograph shows the shaft of the needle maintaining a "target" or "bulls-eye" appearance within the left pedicle. (c) Lateral radiograph shows the needle tip in the anterior one third of the vertebral body. (d) PA prone radiograph shows the needle tip close to the midline. (e) PA prone radiograph shows polymethylmethacrylate (PMM) within the vertebral body. There is slight leakage of PMM adjacent to the left L3/4 disc annulus. (f) Lateral radiograph shows PMM opacification of most of the vertebral body.