Figure 4. Effect of lactate on the accumulation of FDG6P in rat hearts (determined by PET). Hearts were perfused with Krebs buffer plus 11 mM glucose (plus 125 MBq tracer 18FDG) for the first 100 min and subsequently perfused with Krebs buffer plus 11 mM glucose plus 10 mM lactate (plus 125MBq tracer 18FDG). Values are mean±SEM and are expressed in counts per second (cps), n=4 per group.