Figure 1. (Continued from previous page.) (a) MRI of a normal volunteer. T₁-weighted images (TR/TE 650/17) on the left and gradient echo T₂*-weighted images TR/TE (550/15, flip angle 20) on the right. (b), (d) and (e) obtained with the same technique are of Gaucher disease patients with progressively more severe disease. (c) shows T₁- and T₂-weighted turbo spin echo images of the tibae of a Gaucher disease patient.