Figure 3. Cell morphology of control and iodinated contrast media treated neutrophils. Cytospins of (a) control and (b) diatrizoate (20 mg I ml^-1) treated neutrophils at 12 h culture. In control neutrophils, normal neutrophil morphology with a multi-lobulated nucleus is seen (arrow). Following diatrizoate treatment, characteristic morphological signs of neutrophil apoptosis, such as cell shrinkage, nuclear pyknosis and chromatin condensation are demonstrated (arrow). Magnification of figures x 1 000.