Figure 2. A 25-year-old smoker (patient No. 9) presented with dysphasia and a right hemiparesis. Diffusion tensor images (A,B) are normal. The initial trace images (C,D) demonstrate a subtle area of increased signal in the anterior left putamen. The patient was re-imaged at 6 days, which demonstrated disruption of white matter tracts in the left corona radiata (E) with associated trace map changes (F) confirming early ischaemia.